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Home Antibody All anti-CYP2A6 antibodies

Anti-CYP2A6 TRUEMAB Antibody clone 2A8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503827
  • CYP2A6 (Cytochrome P450 2A6) mouse monoclonal antibody, clone 2A8
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424530) , 20ug
100ul 325 In Stock
CF503827
  • Carrier-free (BSA/glycerol-free) CYP2A6 mouse monoclonal antibody,clone 2A8
100ug $450 3-4 weeks
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WB(1)
IHC(1)
IF(1)
FC(1)
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Also for CYP2A6 (NM_000762)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human CYP2A6(NP_000753) produced in HEK293T cell.
Clone Nameclone 2A8 IsotypeIgG2b
Species ReactivityHuman Concentration0.86 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested Dilutions WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cytochrome P450, family 2, subfamily A, polypeptide 6 (CYP2A6)
Alternative NameCPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB
Database LinkNP_000753
FunctionThis gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq, Jul 2008].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2A6 (RC222995, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2A6.
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA503827)
IF Image
Anti-CYP2A6 mouse monoclonal antibody (TA503827) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CYP2A6(RC222995).
FC Image
HEK293T cells transfected with either RC222995 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CYP2A6 antibody(TA503827), and then analyzed by flow cytometry.

 

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