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Anti-CYP2C9 TRUEMAB Antibody clone 3D2
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for CYP2C9 (NM_000771)
|Full length human recombinant protein of human CYP2C9(NP_000762) produced in HEK293T cell.|
|WB, IHC, FC
||WB 1:2000, IHC 1:150, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 (CYP2C9)|
|CPC9; CYP2C; CYP2C10; CYPIIC9; P450IIC9|
|This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq].|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2C9 (RC220997, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2C9.
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-CYP2C9 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA503776)
HEK293T cells transfected with either RC220997 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CYP2C9 antibody(TA503776), and then analyzed by flow cytometry.