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Home Antibody All anti-CDH2 antibodies

Anti-CDH2 TRUEMAB Antibody Clone OTI3B10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA503775 CDH2 (N Cadherin) mouse monoclonal antibody, clone OTI3B10 (formerly 3B10) 100ul $325 In Stock
LC419743 CDH2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF503775 Carrier-free (BSA/glycerol-free) CDH2 mouse monoclonal antibody, clone OTI3B10 (formerly 3B10) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
CE IVD Logo CE marked antibody of this clone also available.
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WB(1)
IHC(2)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human CDH2(NP_001783) produced in HEK293T cell.
Clone NameClone OTI3B10 IsotypeIgG2a
Species ReactivityHuman Concentration1.1 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:2000, IHC 1:150, FLOW 1:100,
Predicted MW Explanation 97.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cadherin 2, type 1, N-cadherin (neuronal) (CDH2)
Alternative NameCD325; CDHN; CDw325; NCAD
Database LinkNP_001783
Entrez Gene 1000 Human
FunctionThis gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq].
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Arrhythmogenic right ventricular cardiomyopathy (ARVC)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH2 (RC207170, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH2.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CDH2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503775)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-CDH2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503775)
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HEK293T cells transfected with either RC207170 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CDH2 antibody(TA503775), and then analyzed by flow cytometry.
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