Anti-ESR1 Antibody, clone 1B1

Also for ESR1 (NM_000125)

OriGene Data

Immunogen	Full length human recombinant protein of human ESR1(NP_000116) produced in HEK293T cell.
Clone Name	clone 1B1	Isotype	IgG2b
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB 1:2000, IHC 1:150,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens estrogen receptor 1 (ESR1), transcript variant 1
Alternative Name	ER; Era; ESR; ESRA; NR3A1
Database Link	NP_000116
Function	This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008].
Related Pathway	TGF Beta Signaling Pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ESR1 (RC213277, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ESR1.

IHC Image

Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-ESR1 mouse monoclonal antibody. (TA503759)

IHC Image

Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-ESR1 mouse monoclonal antibody. (TA503759)

IHC Image

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-ESR1 mouse monoclonal antibody. (TA503759)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-ESR1 mouse monoclonal antibody. (TA503759)

IHC Image

Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-ESR1 mouse monoclonal antibody. (TA503759)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-ESR1 mouse monoclonal antibody. (TA503759)

IHC Image

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-ESR1 mouse monoclonal antibody. (TA503759)

IHC Image

Immunohistochemical staining of paraffin-embedded Human tonsil using anti-ESR1 mouse monoclonal antibody. (TA503759)

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Anti-ESR1 TrueMAB Antibody clone 1B1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data