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Home Antibody All anti-SIRT6 antibodies

Anti-SIRT6 TRUEMAB Antibody Clone OTI1G3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA503670 SIRT6 mouse monoclonal antibody, clone OTI1G3 (formerly 1G3) 100ul
30ul
$379 In Stock
LC402563 SIRT6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF503670 Carrier-free (BSA/glycerol-free) SIRT6 mouse monoclonal antibody, clone OTI1G3 (formerly 1G3) 100ug $450 3-4 weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IF(1)
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Also for SIRT6 (NM_016539)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 88-352 of human SIRT6(NP_057623) produced in E.coli.
Clone NameClone OTI1G3 IsotypeIgG1
Species ReactivityHuman Concentration0.6 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:500~2000, IF 1:100,
Predicted MW Explanation 38.9 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens sirtuin 6 (SIRT6), transcript variant 1
Alternative NameSIR2L6
Database LinkNP_057623
Entrez Gene 51548 Human
FunctionThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIRT6 (RC202833, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRT6.
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Anti-SIRT6 mouse monoclonal antibody (TA503670) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SIRT6(RC202833).
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