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Home Antibody All anti-TP53I3 antibodies

Anti-TP53I3 TRUEMAB Antibody clone 3E3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503590
  • TP53I3 (PIG3) mouse monoclonal antibody, clone 3E3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC407779) , 20ug
100ul 325 In Stock
CF503590
  • Carrier-free (BSA/glycerol-free) TP53I3 mouse monoclonal antibody,clone 3E3
100ug $450 3-4 weeks
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WB(1)
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Also for TP53I3 (NM_147184)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human TP53I3(NP_671713) produced in HEK293T cell.
Clone Nameclone 3E3 IsotypeIgG1
Species ReactivityHuman Concentration0.80 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:2000,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens tumor protein p53 inducible protein 3 (TP53I3), transcript variant 2
Alternative NamePIG3
Database LinkNP_671713
FunctionThe protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Related Pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TP53I3 (RC224067, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TP53I3.

 

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