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Anti-PVRL1 TRUEMAB Antibody clone 6D12
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for PVRL1 (NM_002855)
|Full length human recombinant protein of human PVRL1(NP_002846) produced in HEK293T cell.|
|| WB 1:2000, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens poliovirus receptor-related 1 (herpesvirus entry mediator C) (PVRL1), transcript variant 1|
|CD111; CLPED1; ED4; HIgR; HVEC; nectin-1; OFC7; PRR; PRR1; PVRR; PVRR1; SK-12|
|This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]. |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PVRL1 (RC211214, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PVRL1.
HEK293T cells transfected with either RC211214 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PVRL1 antibody(TA503520), and then analyzed by flow cytometry.