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Home Antibody All anti-PDE4B antibodies

Anti-PDE4B TRUEMAB Antibody clone 1B11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503478
  • PDE4B mouse monoclonal antibody,clone 1B11
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400919) , 20ug
100ul 325 In Stock
CF503478
  • Carrier-free (BSA/glycerol-free) PDE4B mouse monoclonal antibody,clone 1B11
100ug $450 3-4 weeks
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WB(1)
FC(1)
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Also for PDE4B (NM_002600)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PDE4B(NP_002591) produced in HEK293T cell.
Clone Nameclone 1B11 IsotypeIgG1
Species ReactivityHuman Concentration0.66 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:500~2000, FLOW 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a
Alternative NameDPDE4; PDE4B5; PDEIVB
Database LinkNP_002591
FunctionThis gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
Related Pathway
Signaling by GPCR

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE4B (RC211956, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE4B.
FC Image
HEK293T cells transfected with either RC211956 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PDE4B antibody(TA503478), and then analyzed by flow cytometry.

 

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