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Home Antibody All anti-PMVK antibodies

Anti-PMVK TRUEMAB Antibody clone 1C12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503447
  • PMVK mouse monoclonal antibody,clone 1C12
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416571) , 20ug
100ul 325 In Stock
CF503447
  • Carrier-free (BSA/glycerol-free) PMVK mouse monoclonal antibody,clone 1C12
100ug $450 3-4 weeks
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WB(1)
IF(1)
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Also for PMVK (NM_006556)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PMVK(NP_006547) produced in HEK293T cell.
Clone Nameclone 1C12 IsotypeIgG2a
Species ReactivityHuman Concentration0.60 mg/ml
Guaranteed Application *WB, IF Suggested Dilutions WB 1:2000, IF 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens phosphomevalonate kinase (PMVK)
Alternative NameHUMPMKI; PMK; PMKA; PMKASE
Database LinkNP_006547
FunctionThis gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMVK (RC202867, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PMVK.
IF Image
Anti-PMVK mouse monoclonal antibody (TA503447) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PMVK(RC202867).

 

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