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Anti-SIRT5 TRUEMAB Antibody clone 2E12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503292
  • SIRT5 mouse monoclonal antibody, clone 2E12
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC415885) , 20ug Explanation
100ul 325 In Stock
CF503292
  • Carrier-free (BSA/glycerol-free) SIRT5 mouse monoclonal antibody, clone 2E12
100ug $450 3-4 weeks
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(1)
FC(1)
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Also for SIRT5 (NM_012241)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human SIRT5 (NP_036373) produced in HEK293T cell.
Clone Nameclone 2E12 IsotypeIgG1
Species ReactivityHuman Concentration0.57 mg/ml
Guaranteed Application *WB, FC Suggested Dilutions WB 1:500, FLOW 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens sirtuin 5 (SIRT5), transcript variant 1
Alternative NameSIR2L5
Database LinkNP_036373
Entrez Gene 23408 Human
FunctionThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2010].
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIRT5 (RC200189, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRT5.
FC Image
HEK293T cells transfected with either RC200189 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SIRT5 antibody(TA503292), and then analyzed by flow cytometry.

 

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