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Home Antibody All anti-SHPK antibodies

Anti-SHPK TRUEMAB Antibody Clone OTI3D7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA503210 SHPK (CARKL) mouse monoclonal antibody, clone OTI3D7 (formerly 3D7) 100ul $325 In Stock
LC415695 SHPK HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF503210 Carrier-free (BSA/glycerol-free) SHPK mouse monoclonal antibody, clone OTI3D7 (formerly 3D7) 100ug $450 3-4 weeks
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human SHPK(NP_037408) produced in HEK293T cell.
Clone NameClone OTI3D7 IsotypeIgG1
Species ReactivityHuman Concentration0.28 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:500, IHC 1:150, IF 1:100,
Predicted MW Explanation 51.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens sedoheptulokinase (SHPK)
Alternative NameCARKL; SHK
Database LinkNP_037408
Entrez Gene 23729 Human
FunctionThe protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SHPK (RC204421, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SHPK.
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-SHPK mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503210)
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Anti-SHPK mouse monoclonal antibody (TA503210) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SHPK(RC204421).
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