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Home Antibody All anti-IRF6 antibodies

Anti-IRF6 TRUEMAB Antibody Clone 2C10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA503159
  • IRF6 mouse monoclonal antibody,clone 2C10
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401852) , 20ug Explanation
100ul $379 In Stock
CF503159
  • Carrier-free (BSA/glycerol-free) IRF6 mouse monoclonal antibody,clone 2C10
100ug $450 3-4 weeks
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WB(2)
IHC(10)
IF(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human IRF6(NP_006138) produced in HEK293T cell.
Clone NameClone 2C10 IsotypeIgG1
Species ReactivityHuman , Dog , Rat Concentration0.54 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
Predicted MW Explanation 52.9 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens interferon regulatory factor 6 (IRF6), transcript variant 1
Alternative NameLPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
Database LinkNP_006138
Entrez Gene 3664 Human
Entrez Gene 364081 Rat
Entrez Gene 480015 Dog
FunctionThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
Related PathwayES Cell Differentiation/IPSTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IRF6 (RC201579, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IRF6.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-IRF6 monoclonal antibody.
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Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503159)
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Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503159)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503159)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503159)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503159)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503159)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503159)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503159)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503159)
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Immunohistochemical staining of paraffin-embedded Human tonsil using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503159)
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Anti-IRF6 mouse monoclonal antibody (TA503159) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IRF6(RC201579).
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HEK293T cells transfected with either RC201579 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-IRF6 antibody(TA503159), and then analyzed by flow cytometry.
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