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Anti-COASY TRUEMAB Antibody Clone OTI3D5
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for COASY (NM_025233)
|Full length human recombinant protein of human COASY (NP_079509) produced in HEK293T cell.|
||WB 1:2000, FLOW 1:100
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens CoA synthase (COASY), transcript variant 1|
|DPCK; NBIA6; NBP; pOV-2; PPAT; UKR1|
Entrez Gene 80347 Human
|Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC 220.127.116.11) and dephospho-CoA kinase (DPCK; EC 18.104.22.168), in prokaryotes (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM]. |
| Pantothenate and CoA biosynthesisMetabolic pathways|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY COASY (RC220733, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-COASY.
Flow cytometric Analysis of Hela cells, using anti-COASY antibody(TA503060),(Red), compared to a nonspecific negative control antibody,(Blue).
Flow cytometric Analysis of Jurkat cells, using anti-COASY antibody(TA503060),(Red), compared to a nonspecific negative control antibody,(Blue).