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Home Antibody All anti-SOCS3 antibodies

Anti-SOCS3 TRUEMAB Antibody clone 8G3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503039
  • SOCS3 mouse monoclonal antibody,clone 8G3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401300) , 20ug
100ul 325 In Stock
CF503039
  • Carrier-free (BSA/glycerol-free) SOCS3 mouse monoclonal antibody,clone 8G3
100ug $450 3-4 weeks
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WB(1)
IHC(1)
IF(1)
FC(1)
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Also for SOCS3 (NM_003955)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human SOCS3(NP_003946) produced in HEK293 cell.
Clone Nameclone 8G3 IsotypeIgG2a
Species ReactivityHuman Concentration0.97 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens suppressor of cytokine signaling 3 (SOCS3)
Alternative NameATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3
Database LinkNP_003946
FunctionThis gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq].
Related Pathway
Adipogenesis
EGFR1 Signaling Pathway
Jak-STAT signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SOCS3 (RC209305, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SOCS3.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-SOCS3 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA503039)
IF Image
Anti-SOCS3 mouse monoclonal antibody (TA503039) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SOCS3(RC209305).
FC Image
HEK293T cells transfected with either RC209305 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SOCS3 antibody(TA503039), and then analyzed by flow cytometry.

 

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