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Home Antibody All anti-MGLL antibodies

Anti-MGLL TRUEMAB Antibody Clone OTI 2B6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA502973 MGLL (Monoacylglycerol Lipase) mouse monoclonal antibody, clone OTI 2B6 (formerly 2B6) 100ul $325 In Stock
LC402124 MGLL HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502973 Carrier-free (BSA/glycerol-free) MGLL mouse monoclonal antibody, clone OTI 2B6 (formerly 2B6) 100ug $450 3-4 weeks
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WB(1)
IHC(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human MGLL (NP_009214) produced in HEK293T cell.
Clone NameClone OTI 2B6 IsotypeIgG1
Species ReactivityHuman Concentration0.44 mg/ml
Guaranteed Application *WB, IHC, FC Suggested Dilutions WB 1:2000, IHC 1:150, FLOW 1:100,
Predicted MW Explanation 34.1 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens monoglyceride lipase (MGLL), transcript variant 1
Alternative NameHU-K5; HUK5; MAGL; MGL
Database LinkNP_009214
Entrez Gene 11343 Human
FunctionThis gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012].
Related PathwayProteaseDruggable Genome Glycerolipid metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MGLL (RC218358, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MGLL.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-MGLL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502973)
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HEK293T cells transfected with either RC218358 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-MGLL antibody(TA502973), and then analyzed by flow cytometry.
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