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Home Antibody All anti-RPS6KB1 antibodies

Anti-RPS6KB1 TRUEMAB Antibody Clone 1G4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA502913
  • RPS6KB1 (S6K) mouse monoclonal antibody, Clone 1G4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401097) , 20ug Explanation
100ul 325 In Stock
CF502913
  • Carrier-free (BSA/glycerol-free) RPS6KB1 mouse monoclonal antibody,clone 1G4
100ug $450 3-4 weeks
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(2)
IHC(3)
IF(1)
FC(2)
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Also for RPS6KB1 (NM_003161)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human RPS6KB1(NP_003152) produced in HEK293T cell.
Clone NameClone 1G4 IsotypeIgG1
Species ReactivityHuman Concentration0.71 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
Predicted MW Explanation 59 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1), transcript variant 1
Alternative Namep70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A
Database LinkNP_003152
Entrez Gene 6198 Human
FunctionThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome ErbB signaling pathwaymTOR signaling pathwayTGF-beta signaling pathwayFc gamma R-mediated phagocytosisInsulin signaling pathwayAcute myeloid leukemiaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RPS6KB1 (RC217324, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RPS6KB1.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-RPS6KB1 monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-RPS6KB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502913)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-RPS6KB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502913)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-RPS6KB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502913)
IF Image
Anti-RPS6KB1 mouse monoclonal antibody (TA502913) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RPS6KB1(RC217324).
FC Image
HEK293T cells transfected with either RC217324 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-RPS6KB1 antibody(TA502913), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-RPS6KB1 antibody(TA502913),(Red), compared to a nonspecific negative control antibody,(Blue).

 

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