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Home Antibody All anti-PPM1B antibodies

Anti-PPM1B TRUEMAB Antibody Clone OTI3E8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502900 PPM1B mouse monoclonal antibody, clone OTI3E8 (formerly 3E8) 100ul $325 In Stock
LC419156 PPM1B HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502900 Carrier-free (BSA/glycerol-free) PPM1B mouse monoclonal antibody, clone OTI3E8 (formerly 3E8) 100ug $450 3-4 weeks
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WB(1)
IHC(2)
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Also for PPM1B (NM_002706)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PPM1B(NP_002697) produced in HEK293 cell.
Clone NameClone OTI3E8 IsotypeIgG2a
Species ReactivityHuman Concentration0.63 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB 1:2000, IHC 1:150,
Predicted MW Explanation 52.5 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens protein phosphatase, Mg2+/Mn2+ dependent, 1B (PPM1B), transcript variant 1
Alternative NamePP2C-beta; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX
Database LinkNP_002697
Entrez Gene 5495 Human
FunctionThe protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq].
Related PathwayPhosphataseStem cell - PluripotencyDruggable Genome MAPK signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPM1B (RC212918, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PPM1B.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PPM1B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502900)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PPM1B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502900)
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