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Home Antibody All anti-FGFR2 antibodies

Anti-FGFR2 CONJUGATED Antibody Clone 3F8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA502799S
  • FGFR2 mouse monoclonal antibody,clone 3F8
30ul 120 In Stock
CF502799
  • Carrier-free (BSA/glycerol-free) FGFR2 mouse monoclonal antibody,clone 3F8
30ulug $450 3 Days
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Also for FGFR2 (NM_000141)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human FGFR2(NP_000132) produced in HEK293T cell.
Clone NameClone 3F8 IsotypeIgG2a
Species ReactivityHuman Concentration0.93mg/ml
Guaranteed Application * Suggested Dilutions
Buffer
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens fibroblast growth factor receptor 2 (FGFR2), transcript variant 1
Alternative NameBBDS; BEK; BFR-1; CD332; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25
Database LinkNP_000132
FunctionThe protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq].
Related Pathway
MAPK signaling pathway

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