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Home Antibody All anti-FGFR2 antibodies

Anti-FGFR2 CONJUGATED Antibody Clone OTI3F8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502799S FGFR2 mouse monoclonal antibody,clone 3F8 30ul $120 In Stock
CF502799 Carrier-free (BSA/glycerol-free) FGFR2 mouse monoclonal antibody, clone OTI3F8 (formerly 3F8) 30ulug $450 3 Days

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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Also for FGFR2 (NM_000141)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human FGFR2(NP_000132) produced in HEK293T cell.
Clone NameClone OTI3F8 IsotypeIgG2a
Species ReactivityHuman Concentration0.93 mg/ml
Guaranteed Application * Suggested Dilutions
Buffer
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens fibroblast growth factor receptor 2 (FGFR2), transcript variant 1
Alternative NameBBDS; BEK; BFR-1; CD332; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25
Database LinkNP_000132
FunctionThe protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq].
Related PathwayProtein KinaseSecreted ProteinTransmembraneDruggable Genome MAPK signaling pathwayEndocytosisRegulation of actin cytoskeletonPathways in cancerProstate cancer

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* OriGene provides validated application data and protocol, with money back guarantee.

 

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