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Home Antibody All anti-ITM2B antibodies

Anti-ITM2B TRUEMAB Antibody clone 1C11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA502734
  • ITM2B mouse monoclonal antibody, clone 1C11
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC411840) , 20ug Explanation
100ul 379 In Stock
CF502734
  • Carrier-free (BSA/glycerol-free) ITM2B mouse monoclonal antibody, clone 1C11
100ug $450 3-4 weeks
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WB(1)
IHC(1)
FC(2)
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Also for ITM2B (NM_021999)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human ITM2B (NP_068839) produced in HEK293T cell.
Clone Nameclone 1C11 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:2000, IHC 1:150, FLOW 1:100
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens integral membrane protein 2B (ITM2B)
Alternative NameABRI; BRI; BRI2; BRICD2B; E25B; E3-16; FBD; imBRI2
Database LinkNP_068839
Entrez Gene 9445 Human
FunctionAmyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq].
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ITM2B (RC202377, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ITM2B.
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-ITM2B mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA502734)
FC Image
Flow cytometric Analysis of Hela cells, using anti-ITM2B antibody(TA502734),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-ITM2B antibody(TA502734),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).

 

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