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Home Antibody All anti-BECN1 antibodies

Anti-BECN1 TRUEMAB Antibody Clone OTI2D4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA502618 BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI2D4 (formerly 2D4) 100ul $325 In Stock
LC401239 BECN1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502618 Carrier-free (BSA/glycerol-free) BECN1 mouse monoclonal antibody, clone OTI2D4 (formerly 2D4) 100ug $450 3-4 weeks
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WB(1)
IF(1)
FC(2)
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Also for BECN1 (NM_003766)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human BECN1 (NP_003757) produced in HEK293T cell.
Clone NameClone OTI2D4 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100
Predicted MW Explanation 51.7 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens beclin 1, autophagy related (BECN1)
Alternative NameATG6; beclin1; VPS30
Database LinkNP_003757
Entrez Gene 8678 Human
FunctionBeclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).[supplied by OMIM].
Related PathwayDruggable Genome Regulation of autophagy

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BECN1 (RC201629, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BECN1.
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Anti-BECN1 mouse monoclonal antibody (TA502618) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BECN1(RC201629).
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Flow cytometric Analysis of Hela cells, using anti-BECN1 antibody(TA502618),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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Flow cytometric Analysis of Jurkat cells, using anti-BECN1 antibody(TA502618),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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