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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-GBA3 antibodies

Anti-GBA3 TrueMAB Antibody clone 1F1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA502602
  • Purified GBA3 mouse monoclonal antibody, clone 1F1
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402815) , 20ug
 100ul $379 In Stock Add to Shopping Cart
CF502602
  • Carrier-free (BSA/glycerol-free) GBA3 mouse monoclonal antibody, clone 1F1
100ug $450 3-4 weeks Add to Shopping Cart
WB(2)
IHC(16)
FC(3)
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Also for GBA3 (NM_020973)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens glucosidase, beta, acid 3 (cytosolic) (GBA3), transcript variant 1
Synonyms:CBGL1; GLUC; KLrP
ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-150 and 370-469 of human GBA3 (NP_066024) produced in E.coli.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Nameclone 1F1 IsotypeIgG2a
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, FLOW 1:100
BackgroundGBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).[supplied by OMIM].
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GBA3 (RC211035, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GBA3.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-GBA3 monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-GBA3 mouse monoclonal antibody. (TA502602)
FC Image
HEK293T cells transfected with either RC211035 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-GBA3 antibody(TA502602), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Hela cells, using anti-GBA3 antibody(TA502602),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-GBA3 antibody(TA502602),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).

 

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