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Anti-CAT TRUEMAB Antibody clone 1B8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA502564
  • CAT (Catalase) mouse monoclonal antibody, clone 1B8
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419766) , 20ug Explanation
100ul $325 In Stock
CF502564
  • Carrier-free (BSA/glycerol-free) CAT mouse monoclonal antibody, clone 1B8
100ug $450 3-4 weeks
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WB(2)
IHC(11)
IF(1)
FC(2)

OriGene Data

ImmunogenFull length human recombinant protein of human CAT (NP_111743) produced in HEK293T cell.
Clone Nameclone 1B8 IsotypeIgG1
Species ReactivityHuman, Monkey Concentration0.71 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Predicted MW Explanation 59.6 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens catalase (CAT)
Alternative NameMGC138422; MGC138424
Database LinkNP_001743
Entrez Gene 847 Human
Entrez Gene 717406 Monkey
FunctionThis gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq].
Related PathwayDruggable Genome Tryptophan metabolismMethane metabolismMetabolic pathwaysAmyotrophic lateral sclerosis (ALS)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CAT (RC210763, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CAT.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CAT monoclonal antibody.
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502564)
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Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502564)
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Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502564)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502564)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502564)
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Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502564)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502564)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502564)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502564)
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Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502564)
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-CAT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502564)
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Anti-CAT mouse monoclonal antibody (TA502564) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CAT(RC210763).
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Flow cytometric Analysis of Hela cells, using anti-CAT antibody(TA502564),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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Flow cytometric Analysis of Jurkat cells, using anti-CAT antibody(TA502564),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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