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Home Antibody All anti-CTNNB1 antibodies

Anti-CTNNB1 TRUEMAB Antibody clone 3F9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA502407
  • CTNNB1 mouse monoclonal antibody, clone 3F9
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419662) , 20ug Explanation
100ul 325 In Stock
CF502407
  • Carrier-free (BSA/glycerol-free) CTNNB1 mouse monoclonal antibody, clone 3F9
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(3)
IHC(3)
FC(2)
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Also for CTNNB1 (NM_001904)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human CTNNB1 (NP_001895) produced in HEK293T cell.
Clone Nameclone 3F9 IsotypeIgG1
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration0.53 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, FLOW 1:100,
Predicted MW Explanation 85.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1
Alternative Namearmadillo; CTNNB; MRD19
Database LinkNP_001895
Entrez Gene 1499 Human
Entrez Gene 12387 Mouse
Entrez Gene 84353 Rat
Entrez Gene 574265 Monkey
Entrez Gene 477032 Dog
FunctionThe protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
Related PathwayES Cell Differentiation/IPSTranscription FactorsDruggable Genome Wnt signaling pathwayFocal adhesionAdherens junctionTight junctionLeukocyte transendothelial migrationMelanogenesisMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CTNNB1 (RC208947, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CTNNB1.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CTNNB1 monoclonal antibody.
WB Image
Western blot analysis of extracts (10ug) from 9 Human tissue by using anti-CTNNB1 monoclonal antibody at 1:200 (1: Testis; 2: Omentum; 3: Uterus; 4: Breast; 5: Brain; 6: Liver; 7: Ovary; 8: Thyroid gland; 9: Colon).
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-CTNNB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502407)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-CTNNB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502407)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CTNNB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502407)
FC Image
HEK293T cells transfected with either RC208947 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CTNNB1 antibody(TA502407), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Hela cells, using anti-CTNNB1 antibody(TA502407),(Red), compared to a nonspecific negative control antibody,(Blue).

 

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