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Home Antibody All anti-DTNA antibodies

Anti-DTNA TRUEMAB Antibody Clone OTI2F9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502258 DTNA (Dystrobrevin alpha) mouse monoclonal antibody, clone OTI2F9 (formerly 2F9) 100ul $325 In Stock
LC409817 DTNA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502258 Carrier-free (BSA/glycerol-free) DTNA mouse monoclonal antibody, clone OTI2F9 (formerly 2F9) 100ug $450 3-4 weeks
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WB(2)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human DTNA (NP_116761) produced in HEK293T cell.
Clone NameClone OTI2F9 IsotypeIgG2a
Species ReactivityHuman, Monkey Concentration0.72 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:500~2000, FLOW 1:100
Predicted MW Explanation 58.7 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens dystrobrevin, alpha (DTNA), transcript variant 5
Alternative NameD18S892E; DRP3; DTN; DTN-A; LVNC1
Database LinkNP_116761
Entrez Gene 1837 Human
Entrez Gene 707887 Monkey
FunctionThe protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DTNA (RC223952, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DTNA.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-DTNA monoclonal antibody.
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HEK293T cells transfected with either RC223952 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-DTNA antibody(TA502258), and then analyzed by flow cytometry.
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