Anti-LMAN1 Antibody, clone 1C5

Also for LMAN1 (NM_005570)

OriGene Data

Immunogen	Full length human recombinant protein of human LMAN1(NP_005561) produced in Hek293T cell.
Clone Name	clone 1C5	Isotype	IgG1
Species Reactivity	Human, Monkey	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC, FC	Suggested Dilutions	WB 1:500~2000, IHC 1:150, FLOW 1:100,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens lectin, mannose-binding, 1 (LMAN1)
Alternative Name	ERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60
Database Link	NP_005561
Function	The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq].
Related Pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMAN1 (RC207088, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LMAN1.

WB Image

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-LMAN1 monoclonal antibody.

IHC Image

Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-LMAN1 mouse monoclonal antibody. (TA502237)

IHC Image

Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-LMAN1 mouse monoclonal antibody. (TA502237)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-LMAN1 mouse monoclonal antibody. (TA502237)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-LMAN1 mouse monoclonal antibody. (TA502237)

IHC Image

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-LMAN1 mouse monoclonal antibody. (TA502237)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-LMAN1 mouse monoclonal antibody. (TA502237)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-LMAN1 mouse monoclonal antibody. (TA502237)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-LMAN1 mouse monoclonal antibody. (TA502237)

FC Image

Flow cytometric Analysis of Hela cells, using anti-LMAN1 antibody(TA502237),(Red), compared to a nonspecific negative control antibody,(Blue).

FC Image

Flow cytometric Analysis of Jurkat cells, using anti-LMAN1 antibody(TA502237),(Red), compared to a nonspecific negative control antibody,(Blue).

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OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-LMAN1 TrueMAB Antibody clone 1C5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data