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Home Antibody All anti-BIRC5 antibodies

Anti-BIRC5 TRUEMAB Antibody Clone OTI6H5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA502235 Purified BIRC5/Survivin mouse monoclonal antibody, clone OTI6H5 (formerly 6H5) 100ul $325 In Stock
LC400469 BIRC5 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502235 Carrier-free (BSA/glycerol-free) BIRC5/Survivin mouse monoclonal antibody, clone OTI6H5 (formerly 6H5) 100ug $450 3-4 weeks
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WB(1)
IF(1)
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Also for BIRC5 (NM_001168)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human BIRC5 (NP_001159) produced in HEK293T cell.
Clone NameClone OTI6H5 IsotypeIgG1
Species ReactivityHuman Concentration0.52 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:500, IF 1:100,
Predicted MW Explanation 16.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 1
Alternative NameAPI4; EPR-1
Database LinkNP_001159
Entrez Gene 332 Human
FunctionThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq].
Related PathwayStem cell - PluripotencyDruggable Genome Pathways in cancerColorectal cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BIRC5 (RC205935, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BIRC5 .
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Anti-BIRC5 mouse monoclonal antibody (TA502235) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BIRC5 (RC205935).
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