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Home Antibody All anti-BIRC5 antibodies

Anti-BIRC5 TRUEMAB Antibody clone 2D3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA502234
  • Purified BIRC5/Survivin mouse monoclonal antibody,clone 2D3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400469) , 20ug
100ul $325 In Stock
CF502234
  • Carrier-free (BSA/glycerol-free) BIRC5/Survivin mouse monoclonal antibody,clone 2D3
100ug $450 3-4 weeks
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WB(1)
IF(1)
FC(1)
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Also for BIRC5 (NM_001168)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human BIRC5(NP_001159) produced in HEK293T cell.
Clone Nameclone 2D3 IsotypeIgG1
Species ReactivityHuman Concentration0.54 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 1
Alternative NameAPI4; EPR-1
Database LinkNP_001159
FunctionThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq].
Related Pathway
Apoptosis
Cell cycle

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BIRC5 (RC205935, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BIRC5.
IF Image
Anti-BIRC5 mouse monoclonal antibody (TA502234) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BIRC5(RC205935).
FC Image
HEK293T cells transfected with either RC205935 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-BIRC5 antibody(TA502234), and then analyzed by flow cytometry.

 

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