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Anti-MMAB TRUEMAB Antibody Clone OTI2A7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA502179 MMAB mouse monoclonal antibody, clone OTI2A7 (formerly 2A7) 100ul 325
In Stock
LC409455 MMAB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502179 Carrier-free (BSA/glycerol-free) MMAB mouse monoclonal antibody, clone OTI2A7 (formerly 2A7) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human MMAB (NP_443077) produced in HEK293T cell.
Clone NameClone OTI2A7 IsotypeIgG1
Species ReactivityHuman Concentration0.86 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:2000, FLOW 1:100
Predicted MW Explanation 24.0 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens methylmalonic aciduria (cobalamin deficiency) cblB type (MMAB), transcript variant 1
Alternative NameATR; cblB; CFAP23; cob
Database LinkNP_443077
Entrez Gene 326625 Human
FunctionThis gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. [provided by RefSeq].
Related Pathway Porphyrin and chlorophyll metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMAB (RC204290, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMAB.
HEK293T cells transfected with either RC204290 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-MMAB antibody(TA502179), and then analyzed by flow cytometry.
Flow cytometric Analysis of Jurkat cells, using anti-MMAB antibody(TA502179),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).


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