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Home Antibody All anti-GCKR antibodies

Anti-GCKR TRUEMAB Antibody Clone OTI1E7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA502152 GCKR mouse monoclonal antibody, clone OTI1E7 (formerly 1E7) 100ul $379 In Stock
LC400576 GCKR HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502152 Carrier-free (BSA/glycerol-free) GCKR mouse monoclonal antibody, clone OTI1E7 (formerly 1E7) 100ug $450 4 Weeks
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WB(2)
IHC(2)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human GCKR (NP_001417) produced in HEK293T cell.
Clone NameClone OTI1E7 IsotypeIgG1
Species ReactivityHuman Concentration0.73 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:2000, IHC 1:150, IF 1:100,
Predicted MW Explanation 68.5 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens glucokinase regulator (GCKR)
Alternative NameFGQTL5; GKRP
Database LinkNP_001477
Entrez Gene 2646 Human
FunctionThis gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GCKR (RC214230, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GCKR.
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WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-GCKR monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).(1:200)
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IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-GCKR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502152)
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IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-GCKR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502152)
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IF Image
Anti-GCKR mouse monoclonal antibody (TA502152) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GCKR(RC214230).
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