Anti-MYD88 Antibody, clone 1B8

Also for MYD88 (NM_002468)

Gene Name	Homo sapiens myeloid differentiation primary response 88 (MYD88), transcript variant 2
Synonyms:	MYD88D
Immunogen	Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Name	clone 1B8	Isotype	IgG1
Species Reactivity	Human , Rat , Monkey	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *	WB, IHC, IF, FC	Suggested Dilutions	WB 1:1000~2000, IHC 1:150, IF 1:100, FLOW 1:100,
Background	This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq].
Related Pathway	Toll-like receptor signaling pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MYD88 (RC202253, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MYD88.

WB Image

Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-MYD88 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-MYD88 mouse monoclonal antibody. (TA502118)

IF Image

Anti-MYD88 mouse monoclonal antibody (TA502118) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MYD88(RC202253).

FC Image

HEK293T cells transfected with either RC202253 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-MYD88 antibody(TA502118), and then analyzed by flow cytometry.

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Anti-MYD88 TrueMAB Antibody clone 1B8

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