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Anti-KEAP1 TRUEMAB Antibody clone 1A1
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for KEAP1 (NM_203500)
|Full length human recombinant protein of human KEAP1 (NP_987096) produced in HEK293T cell.|
||WB 1:2000, FLOW 1:100
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens kelch-like ECH-associated protein 1 (KEAP1), transcript variant 1|
Entrez Gene 9817 Human
|This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq].|
|Transcription Factors Ubiquitin mediated proteolysis|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KEAP1 (RC202189, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KEAP1.
HEK293T cells transfected with either RC202189 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-KEAP1 antibody(TA502056), and then analyzed by flow cytometry.