This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Related Pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PANK3 (RC203696, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PANK3.
HEK293T cells transfected with either RC203696 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PANK3 antibody(TA502037), and then analyzed by flow cytometry.
Flow cytometric Analysis of Hela cells, using anti-PANK3 antibody(TA502037),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
Flow cytometric Analysis of Jurkat cells, using anti-PANK3 antibody(TA502037),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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