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Home Antibody All anti-HDAC6 antibodies

Anti-HDAC6 TRUEMAB Antibody Clone OTI1B3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502001 HDAC6 mouse monoclonal antibody, clone OTI1B3 (formerly 1B3) 100ul $325 In Stock
LC401822 HDAC6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502001 Carrier-free (BSA/glycerol-free) HDAC6 mouse monoclonal antibody, clone OTI1B3 (formerly 1B3) 100ug $450 3-4 weeks
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WB(2)
IHC(3)
IF(1)
FC(1)
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Also for HDAC6 (NM_006044)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human HDAC6 (NP_006035) produced in HEK293T cell.
Clone NameClone OTI1B3 IsotypeIgG1
Species ReactivityHuman, Monkey Concentration0.65 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Predicted MW Explanation 131.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens histone deacetylase 6 (HDAC6)
Alternative NameCPBHM; HD6; JM21; PPP1R90
Database LinkNP_006035
Entrez Gene 10013 Human
Entrez Gene 711363 Monkey
FunctionHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq].
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HDAC6 (RC209649, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HDAC6.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-HDAC6 monoclonal antibody.
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-HDAC6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502001)
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-HDAC6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502001)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-HDAC6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502001)
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Anti-HDAC6 mouse monoclonal antibody (TA502001) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HDAC6(RC209649).
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HEK293T cells transfected with either RC209649 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-HDAC6 antibody(TA502001), and then analyzed by flow cytometry.
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