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Home Antibody All anti-SPR antibodies

Anti-SPR TRUEMAB Antibody clone 3C8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA501962
  • SPR mouse monoclonal antibody, clone 3C8
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401086) , 20ug
100ul $325 In Stock
CF501962
  • Carrier-free (BSA/glycerol-free) SPR mouse monoclonal antibody, clone 3C8
100ug $450 3-4 weeks
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WB(1)
FC(2)
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Also for SPR (NM_003124)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human SPR (NP_003115) produced in HEK293T cell.
Clone Nameclone 3C8 IsotypeIgG1
Species ReactivityHuman Concentration0.72 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:2000, FLOW 1:100
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (SPR)
Alternative NameSDR38C1
Database LinkNP_003115
FunctionThis gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq].
Related Pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (RC205679, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.
FC Image
HEK293T cells transfected with either RC205679 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SPR antibody(TA501962), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-SPR antibody(TA501962),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).

 

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