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Anti-IVD TRUEMAB Antibody clone 1F1
TrueMAB Antibodies - Made against Authentic Protein Antigens
|Full length human recombinant protein of human IVD (NP_002612) produced in HEK293T cell.|
||WB 1:2000, FLOW 1:100
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens isovaleryl-CoA dehydrogenase (IVD), transcript variant 1|
Entrez Gene 3712 Human
|Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].|
|Druggable Genome Valine, leucine and isoleucine degradationMetabolic pathways|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IVD (RC229217, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IVD.
HEK293T cells transfected with either RC201077 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-IVD antibody(TA501670), and then analyzed by flow cytometry.