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Anti-QPRT TRUEMAB Antibody Clone OTI4E6
TrueMAB Antibodies - Made against Authentic Protein Antigens
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Also for QPRT (NM_014298)
|Full length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell.|
|WB, IHC, FC
||WB 1:500~2000, IHC 1:150, FLOW 1:100
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens quinolinate phosphoribosyltransferase (QPRT)|
Entrez Gene 23475 Human
|This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.|
| Nicotinate and nicotinamide metabolismMetabolic pathways|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY QPRT (RC202960, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-QPRT.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-QPRT monoclonal antibody.
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-QPRT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501522)
Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-QPRT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501522)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-QPRT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501522)
HEK293T cells transfected with either RC202960 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-QPRT antibody(TA501522), and then analyzed by flow cytometry.