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Home Antibody All anti-NUMB antibodies

Anti-NUMB TRUEMAB Antibody Clone OTI2C4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA501518 NUMB mouse monoclonal antibody, clone OTI2C4 (formerly 2C4) 100ul $325 In Stock
LC401229 NUMB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501518 Carrier-free (BSA/glycerol-free) NUMB mouse monoclonal antibody, clone OTI2C4 (formerly 2C4) 100ug $450 3-4 weeks
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WB(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human NUMB (NP_003735) produced in HEK293T cell.
Clone NameClone OTI2C4 IsotypeIgG1
Species ReactivityHuman Concentration0.76 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:500, FLOW 1:100
Predicted MW Explanation 69.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens numb homolog (Drosophila) (NUMB), transcript variant 3
Alternative NameC14orf41; c14_5527; S171
Database LinkNP_003735
Entrez Gene 8650 Human
FunctionThe protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.
Related Pathway Notch signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NUMB (RC216230, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NUMB.
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HEK293T cells transfected with either RC216230 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-NUMB antibody(TA501518), and then analyzed by flow cytometry.
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