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Anti-PAICS TRUEMAB Antibody Clone OTI1B4
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for PAICS (NM_006452)
|Full length human recombinant protein of human PAICS (NP_006443) produced in HEK293T cell.|
|WB, IF, FC
||WB 1:2000, IF 1:100, FLOW 1:100
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 2|
|ADE2; ADE2H1; AIRC; PAIS|
Entrez Gene 10606 Human
|This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].|
|Druggable Genome Purine metabolismMetabolic pathways|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PAICS (RC215225, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PAICS.
Western blot analysis of extracts (10ug) from 5 different cell lines by using anti-PAICS monoclonal antibody at 1:200 dilution.
Anti-PAICS mouse monoclonal antibody (TA501470) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PAICS(RC215225).
HEK293T cells transfected with either RC215225 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PAICS antibody(TA501470), and then analyzed by flow cytometry.
Flow cytometric Analysis of Jurkat cells, using anti-PAICS antibody(TA501470),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).