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 Home All anti-EIF2S1 antibodies

Anti-EIF2S1 TrueMAB Antibody clone 5D10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA501401
  • anti-EIF2S1 mouse monoclonal antibody, clone 5D10
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401321) , 20ug
 100ul $325 In Stock
CF501401
  • Carrier-free (BSA/glycerol-free) EIF2S1 mouse monoclonal antibody, clone 5D10
100ug $450 3-4 weeks
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
 30ul
$100
$50*		 In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IHC(3)
IF(1)
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Also for EIF2S1 (NM_004094)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human EIF2S1 (NP_004085) produced in HEK293T cell.
Clone Nameclone 5D10 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:2000, IHC 1:50, IF 1:100,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target NameHomo sapiens eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1)
Alternative NameEIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A
Database LinkNP_004085
FunctionThe translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EIF2S1 (RC200368, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EIF2S1.
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-EIF2S1 mouse monoclonal antibody. (TA501401, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-EIF2S1 mouse monoclonal antibody. (TA501401, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Human thyroid tissue using anti-EIF2S1 mouse monoclonal antibody. (TA501401, Dilution 1:50)
IF Image
Anti-EIF2S1 mouse monoclonal antibody (TA501401) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY EIF2S1(RC200368).

 

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