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Home Antibody All anti-PEX5 antibodies

Anti-PEX5 TRUEMAB Antibody Clone OTI6C4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA501390 anti-PEX5 mouse monoclonal antibody, clone OTI6C4 (formerly 6C4) 100ul $325 In Stock
LC424800 PEX5 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501390 Carrier-free (BSA/glycerol-free) PEX5 mouse monoclonal antibody, clone OTI6C4 (formerly 6C4) 100ug $450 3-4 weeks
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WB(1)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human PEX5 (NP_000310) produced in HEK293T cell.
Clone NameClone OTI6C4 IsotypeIgG2b
Species ReactivityHuman Concentration0.91 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:2000, IF 1:100,
Predicted MW Explanation 69.7 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens peroxisomal biogenesis factor 5 (PEX5), transcript variant 2
Alternative NamePBD2A; PBD2B; PTS1-BP; PTS1R; PXR1
Database LinkNP_000310
Entrez Gene 5830 Human
FunctionThe product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PEX5 (RC202062, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PEX5.
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Anti-PEX5 mouse monoclonal antibody (TA501390) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PEX5(RC202062).
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