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Home Antibody All anti-TBXAS1 antibodies

Anti-TBXAS1 TRUEMAB Antibody Clone OTI1B8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA501364 anti-TBXAS1 (Thromboxane synthase) mouse monoclonal antibody, clone OTI1B8 (formerly 1B8) 100ul $325 In Stock
LC420741 TBXAS1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501364 Carrier-free (BSA/glycerol-free) TBXAS1 mouse monoclonal antibody, clone OTI1B8 (formerly 1B8) 100ug $450 3-4 weeks
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WB(1)
IF(1)
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Also for TBXAS1 (NM_001061)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human TBXAS1 (NP_001052) produced in HEK293T cell.
Clone NameClone OTI1B8 IsotypeIgG2a
Species ReactivityHuman Concentration0.94 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:2000, IF 1:100
Predicted MW Explanation 60.5 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens thromboxane A synthase 1 (platelet) (TBXAS1), transcript variant 1
Alternative NameBDPLT14; CYP5; CYP5A1; GHOSAL; THAS; TS; TXAS; TXS
Database LinkNP_001052
Entrez Gene 6916 Human
Function?This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayP450Druggable Genome Arachidonic acid metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TBXAS1 (RC208028, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TBXAS1.
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Anti-TBXAS1 mouse monoclonal antibody (TA501364) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TBXAS1(RC208028).
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