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Home Antibody All anti-PANK2 antibodies

Anti-PANK2 TRUEMAB Antibody clone 4B3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA501355
  • anti-PANK2 mouse monoclonal antibody, clone 4B3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC406998) , 20ug
100ul 325 In Stock
CF501355
  • Carrier-free (BSA/glycerol-free) PANK2 mouse monoclonal antibody, clone 4B3
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(1)
IF(1)
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Also for PANK2 (NM_153638)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PANK2(NP_705902) produced in HEK293T cell.
Clone Nameclone 4B3 IsotypeIgG2a
Species ReactivityHuman Concentration1.00 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:2000, IHC 1:150, IF 1:100,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens pantothenate kinase 2 (PANK2), transcript variant 1
Alternative NameC20orf48; HARP; HSS; NBIA1; PKAN
Database LinkNP_705902
FunctionThis gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PANK2 (RC215676, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PANK2.
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-PANK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA501355, Dilution 1:50)
IF Image
Anti-PANK2 mouse monoclonal antibody (TA501355) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PANK2(RC215676).

 

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