Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566.
[anti-HA]
Regulation of the PI3-K/Akt Survival Pathway in the Rat Endometrium Biol Reprod, Mar 2013; 88: 79.
[Akt3]
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159.
[LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408.
[JAK2]
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts with the cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 in its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor receptor protein. [provided by RefSeq].
Related Pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SNX9 (RC202822, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SNX9.
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-SNX9 mouse monoclonal antibody. (TA501325, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-SNX9 mouse monoclonal antibody. (TA501325, Dilution 1:50)
HEK293T cells transfected with either RC202822 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SNX9 antibody(TA501325), and then analyzed by flow cytometry.
Flow cytometric Analysis of Jurkat cells, using anti-SNX9 antibody(TA501325),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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