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Anti-GNMT TRUEMAB Antibody Clone OTI8A3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA501276 anti-GNMT mouse monoclonal antibody, clone OTI8A3 (formerly 8A3) 100ul 379
In Stock
LC412848 GNMT HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501276 Carrier-free (BSA/glycerol-free) GNMT mouse monoclonal antibody, clone OTI8A3 (formerly 8A3) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human GNMT (NP_061833) produced in HEK293T cell.
Clone NameClone OTI8A3 IsotypeIgG3
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:200 - 1:1000, Flow 1:100
Predicted MW Explanation 32.6kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.22% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens glycine N-methyltransferase (GNMT)
Alternative NameOTTHUMP00000016412; glycine N-methyltransferase
Database LinkNP_061833
Entrez Gene 27232 Human
FunctionThe protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).
Related PathwayDruggable Genome Glycine, serine and threonine metabolism

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GNMT (RC207497, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GNMT.
Western blot analysis of extracts (10ug) from 7 different cell lines by using anti-GNMT monoclonal antibody.(1:200)
HEK293T cells transfected with either pCMV6-ENTRY GNMT(RC207497)(Red) or empty vector control plasmid(Blue) were immunostained with anti-GNMT mouse monoclonal(TA501276), and then analyzed by flow cytometry.


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