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Anti-CYP1A2 TRUEMAB Antibody clone 2E9
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for CYP1A2 (NM_000761)
|Full length human recombinant protein of human CYP1A2 (NP_000752) produced in HEK293T cell.|
||WB 1:1000, FLOW 1:100
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2)|
|CP12; P3-450; P450(PA)|
|This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq].|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP1A2 (RC221636, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP1A2.
HEK293T cells transfected with either RC221636 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CYP1A2 antibody(TA501197), and then analyzed by flow cytometry.
Flow cytometric Analysis of Hela cells, using anti-CYP1A2 antibody(TA501197),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
Flow cytometric Analysis of Jurkat cells, using anti-CYP1A2 antibody(TA501197),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).