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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-PDE4A antibodies

Anti-PDE4A TrueMAB Antibody clone 1C8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA501192
  • Purified anti-PDE4A mouse monoclonal antibody, clone 1C8
  • FREE positive control: HEK293T cell transient overexpression lysate (LC416800) , 20ug
 100ul $325 In Stock Add to Shopping Cart
CF501192
  • Carrier-free (BSA/glycerol-free) PDE4A mouse monoclonal antibody, clone 1C8
100ug $450 3-4 weeks Add to Shopping Cart
WB(1)
IHC(8)
IF(2)
FC(1)
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Also for PDE4A (NM_006202)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody
Gene NameHomo sapiens phosphodiesterase 4A, cAMP-specific (PDE4A), transcript variant 4
Synonyms:DPDE2; PDE4; PDE46
ImmunogenFull length human recombinant protein of human PDE4A (NP_006193) produced in HEK293T cell.
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Nameclone 1C8 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100
BackgroundCyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE
Related Pathway
Signaling by GPCR

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE4A (RC207765, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE4A .
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-PDE4A mouse monoclonal antibody. (TA501192, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PDE4A mouse monoclonal antibody. (TA501192, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-PDE4A mouse monoclonal antibody. (TA501192, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-PDE4A mouse monoclonal antibody. (TA501192, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-PDE4A mouse monoclonal antibody. (TA501192, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PDE4A mouse monoclonal antibody. (TA501192, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-PDE4A mouse monoclonal antibody. (TA501192, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-PDE4A mouse monoclonal antibody. (TA501192, Dilution 1:50)
IF Image
Anti-PDE4A mouse monoclonal antibody (TA501192) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDE4A (RC207765 ).
IF Image
Immunofluorescent staining of HT29 cells using anti-PDE4A mouse monoclonal antibody (TA501192).
FC Image
HEK293T cells transfected with either RC207765 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PDE4A antibody(TA501192), and then analyzed by flow cytometry.

 

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