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Anti-CYP1A2 TRUEMAB Antibody clone 7A9
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for CYP1A2 (NM_000761)
|Full length human recombinant protein of human CYP1A2 (NP_000752) produced in HEK293T cell.|
||WB 1:500, IF 1:100,
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2)|
|CP12; P3-450; P450(PA)|
|This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.|
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Anti-CYP1A2 mouse monoclonal antibody (TA501157) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CYP1A2(RC221636).