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Anti-PTPRE TRUEMAB Antibody Clone OTI4G2
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for PTPRE (NM_006504)
|Full length human recombinant protein of human PTPRE (NP_006495) produced in HEK293T cell.|
|WB, IF, FC
||WB 1:2000, IF 1:100, FLOW 1:100
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens protein tyrosine phosphatase, receptor type E (PTPRE), transcript variant 1|
|HPTPE; PTPE; R-PTP-EPSILON|
Entrez Gene 5791 Human
|The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic tran signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region,and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.|
|TransmembranePhosphataseDruggable Genome |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTPRE (RC207950, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTPRE.
Anti-PTPRE mouse monoclonal antibody (TA501073) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PTPRE(RC207950 ).
HEK293T cells transfected with either RC207950 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PTPRE antibody(TA501073), and then analyzed by flow cytometry.
Flow cytometric Analysis of Jurkat cells, using anti-PTPRE antibody(TA501073),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
Flow cytometric Analysis of Hela cells, using anti-PTPRE antibody(TA501073),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).