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Home Antibody All anti-IFT57 antibodies

Anti-IFT57 TRUEMAB Antibody Clone 2G3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500917
  • anti-IFT57 (HIPPI) mouse monoclonal antibody, Clone 2G3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402637) , 20ug
100ul 379 In Stock
CF500917
  • Carrier-free (BSA/glycerol-free) IFT57 mouse monoclonal antibody, clone 2G3
100ug $450 3-4 weeks
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WB(1)
IHC(2)
IF(1)
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Also for IFT57 (NM_018010)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human IFT57 (NP_060480) produced in HEK293T cell.
Clone NameClone 2G3 IsotypeIgG1
Species ReactivityHuman Concentration0.71 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:1000, IHC 1:50, IF 1:100,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens intraflagellar transport 57 (IFT57)
Alternative NameESRRBL1; HIPPI; MHS4R2
Database LinkNP_060480
FunctionRequired for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1,leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3'present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IFT57 (RC204116, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IFT57.
IHC Image
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-IFT57 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500917, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of pancreas tissue using anti-IFT57 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500917, Dilution 1:50)
IF Image
Immunofluorescent staining of HepG2 cells using anti-IFT57 mouse monoclonal antibody (TA500917).

 

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