Also for XRCC1 (NM_006297)
|Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1)|
|The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]. |
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